Uses: Pyridine is used as a solvent in organic chemistry and in industrial practice It is used to make medicines, vitamins, food flavorings, pesticides, paints, dyes, rubber products, adhesives, and waterproofing for fabrics
Production: Pyridine can be made from crude coal tar or from other chemicals It can also be formed from the breakdown of many natural materials in the environment
Safety: Pyridine is hazardous and has some unpleasant properties It evaporates into the air very easily It can take several months to years for pyridine to break down into other compounds in the air
Pyridine is a reasonable nucleophile for carbonyl groups and is often used as a catalyst in acylation reactions. ... The nitrogen atom in pyridine is nucleophilic because the lone pair of electrons on nitrogen cannot be delocalised around the ring.
Pyridine is used as a polar, basic, low-reactive solvent, for example in Knoevenagel condensations. It is especially suitable for the dehalogenation, where it acts as the base of the elimination reaction and bonds the resulting hydrogen halide to form a pyridinium salt.
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