Estimating kidney function is challenging and critically ill patients.
Creatinine is a widely used functional biomarker and has substantial shortcomings.
Use of novel functional biomarkers with creatinine provides additional information.
Creatinine could be used for the estimation of muscle mass or clinical outcomes.
New technologies for direct GFR measurement could overcome creatinine limitations.
New technologies for direct GFR measurement could overcome creatinine limitations.Estimating kidney function is challenging and critically ill patients.
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Creatinine is a widely used functional biomarker and has substantial shortcomings.
•
Use of novel functional biomarkers with creatinine provides additional information.
•
Creatinine could be used for the estimation of muscle mass or clinical outcomes.
•
New technologies for direct GFR measurement could overcome creatinine limitations.