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NN DIISOPROPYL EHTHYLAMINE FOR SYNTHESIS
Product Code: RXSOL-60-6605-027

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Product Description

N,N-Diisopropylethylamine may be used in the synthesis of mannosylated ovalbumin peptides. Proton scavenger used in peptide coupling, enolboration, Pd(0)-catalyzed alkoxycarbonylation of allyl phosphates and acetates, and as a catalyst in vinyl sulfone synthesis.

Product Short Description

NN DIISOPROPYL EHTHYLAMINE FOR SYNTHESIS

Product Application

It is commonly used as the hindered base in amide coupling reactions between a carboxylic acid (typically activated, for example, as an acid chloride, as illustrated below) and a nucleophilic amine. As DIPEA is hindered and poorly nucleophilic, it does not compete with the nucleophilic amine in the coupling reaction.

Product Dose

DIPEA is a good base used for deprotonation of carboxylic acid in peptides/amino acids to give you the intermediate carboxylate. It is added based on molar ratio.

Product Note

Diisopropylamine is purified by heating to reflux over sodium hydroxide (NaOH) for 3–12 hr, followed by simple distillation from NaOH. 4. Butyllithium in hexanes (2.5 M) is purchased from Aldrich Chemical Company, Inc., and titrated using diphenylacetic acid.

Other Equivalent Brand

NN DIISOPROPYL EHTHYLAMINE FOR SYNTHESIS

Free Delivery / Supply Locations

Oman, Bahrain, Abu Dhabi, Ajman, Al Ain, Dubai, Ras Al-Khaimah, Fujairah, Sharjah, Umm Al Quwain, Ruwais, Khalifa Port, Jebel Ali, DP WORLD, and all UAE ports...